People at Carnegie
Nicholas Theodore, M.D., M.S.
Co-Director, Clinical Innovation
Ali Uneri, Ph.D.
Co-Director, Research & Innovation
Nitish Thakor, Ph.D.
Co-Director, Innovation & Translation
Carnegie Faculty
Dr. Muyinatu A. Lediju Bell (informally known as "Bisi") leads a highly interdisciplinary research program that integrates optics, acoustics, robotics, electronics, and mechanics, as well as signal processing and medical device design, to engineer and deploy innovative biomedical imaging systems that simultaneously address unmet clinical needs and significantly improve the standard of patient care. As the director of the Photoacoustic and Ultrasonic Systems Engineering (PULSE) Lab, Dr. Bell develops theories, models, and simulations to investigate advanced beamforming techniques for improving ultrasonic and photoacoustic image quality. In parallel, she designs and builds novel light delivery systems for photoacoustic imaging and incorporates medical robots to improve operator maneuverability and enable standardized procedures for more personalized medicine. The technologies developed in her lab are then interfaced with patients to facilitate clinical translation. These technologies have applications in neurosurgical navigation, cardiovascular disease, women’s health, and cancer detection and treatment.
Dr. Bell obtained a PhD in Biomedical Engineering from Duke University and a BS in Mechanical Engineering with a minor in Biomedical Engineering from the Massachusetts Institute of Technology. In addition, she spent a year abroad as an academic visitor at the Institute of Cancer Research and Royal Marsden Hospital in the United Kingdom. Prior to joining the faculty, Dr. Bell was a postdoctoral fellow with the Engineering Research Center for Computer-Integrated Surgical Systems and Technology at Johns Hopkins University. She published over 40 scientific journal articles and conference papers, holds a patent for SLSC beamforming, and is the recipient of numerous awards, grants, and fellowships, including the prestigious NIH K99/R00 Pathway to Independence Award.
Assistant Professor
Dept. of Biomedical Engineering
Dept. of Electrical &Computer Engineering
Johns Hopkins University
Barton Hall 208
3400 N. Charles Street
Baltimore, MD 21218
Email: [email protected]
More information: http://engineering.jhu.g.sjuku.top/pulselab/
Dr. Kai Ding directs the Image Guided Radiation Therapy (IGRT) lab in the Carnegie Center of Surgical Innovation. He is a senior medical physicist in the Department of Radiation Oncology and Molecular Radiation Sciences. His research areas include endoscopic ultrasound, hydrogel spacer, robotics, and proton therapy. Dr. Ding received his Ph.D. in biomedical engineering, at the University of Iowa and did his radiation oncology physics residency at the University of Virginia.
Associate Professor
Department of Radiation Oncology
and Molecular Radiation Sciences
Johns Hopkins University
Johns Hopkins University
401 North Broadway, Suite 1440
Baltimore, MD 21287-0019
Email: [email protected]
More information: Ding Lab
Dr. Nicholas Durr directs the Computational Biophotonics Laboratory in the Carnegie Center for Surgical Innovation. He is an Assistant Professor of Biomedical Engineering at the Whiting School of Engineering and the Johns Hopkins University School of Medicine and the Undergraduate Program Director for the Center of Bioengineering Innovation & Design at Johns Hopkins University. His research focuses on computational biophotonics.
Dr. Durr received his B.S. in Electrical Engineering and Computer Science from the University of California, Berkeley, in 2003, and in 2010 completed his Ph.D. in Biomedical Engineering at the University of Texas at Austin, hook 'em horns. He was a Postdoctoral Fellow at Harvard Medical School in 2010 and an independent investigator at MIT from 2011 to 2014 as a Fellow in the M+Vision Consortium. Before joining Johns Hopkins, he was the Founder and CEO of PlenOptika, a Boston-based startup aimed at commercializing technologies to improve eye care accessibility worldwide.
Assistant Professor
Dept. of Biomedical Engineering
Director of Undergraduate Programs
Center for Bioengineering Innovation & Design
Johns Hopkins University
720 Rutland Avenue
Baltimore, MD 21205
Email: [email protected]
More information: Durr Lab
Muyinatu (Bisi) Bell, Ph.D.
Kai Ding, Ph.D., DABR
Nicholas Durr, Ph.D.
Juan R. Garcia is an Associate Professor at the Johns Hopkins University School of Medicine. He serves as director of the Facial Prosthetics Clinic within the Department of Art as Applied to Medicine, and teaches ophthalmological illustration, medical sculpture and anaplastology. As director of the Facial Prosthetics Clinic, Mr. Garcia crafts custom-made prosthetic substitutes for missing facial and somatic anatomy. This involves creating non-weight bearing silicone appliances for the face and body. These devices are attached to the affected area via adhesives, magnetic components, or an osseointegrated implant system. Additional services provided include: custom ocular prostheses, custom surgical guides using CT scans, surface laser scans, custom silicone implants, medical models and rapid prototyped models. At the Carnegie Center, Juan is the director of the 3D printing core services.
Associate Professor
Dept. of Art as Applied to Medicine
1830 E. Monument St.
Baltimore, MD 21287
Email: [email protected]
Dr. Junghoon Lee is an Associate Professor of Division of Medical Physics in the Department of Radiation Oncology and Molecular Radiation Sciences. He is the director of Medical Image Computing and Analysis (MICA) laboratory, a highly multidisciplinary and collaborative biomedical research lab. His research focuses on image processing and analysis, computer vision, and machine learning with application to medical imaging problems. MICA has pioneered many areas of medical imaging including computed tomography, novel image reconstruction, registration, and segmentation, motion estimation, image-guided interventions, radiotherapy, and surgery, imaging informatics, and image-based outcome prediction in radiotherapy.
Dr. Xingde Li's research interest centers on development of cutting-edge and translational biophotonics technologies that interface and bridge basic engineering research and medical diagnosis and intervention. The research and training involves vertical integration of multiple disciplines, including (but not limited to) optics, electrical engineering, micro-nano technology, biology and clinical medicine. The ultimate goal of our research is to transform our capability of disease detection at early, manageable stages, monitoring therapeutic effects and treatment outcomes, and guiding interventions. The technologies also offer new opportunities for basic research in exploring new frontiers of disease mechanisms, brain function, bio-marker discovery and integrated diagnosis and therapy.
Professor
Dept. of Biomedical Engineering
Dept. of Electrical and Computer Engineering
Johns Hopkins University
Ross Building, Room 731B
720 Rutland Avenue
Baltimore, MD 21205
Phone: 410-955-0075
Email: [email protected]
More information: Biophotonics Imaging Technology Lab (BIT)
Juan Garcia
Junghoon Lee, Ph.D.
Xingde Li, Ph.D.
Dr. Wojtek Zbijewski is a physicist whose research interests include x-ray CT image reconstruction, Monte Carlo modeling, and the development of novel imaging systems. He leads activities in imaging system instrumentation throughout the I-STAR Lab, including cone-beam CT, photon counting CT, and and advanced volumetric imaging for extremities imaging in musculoskeletal radiology, orthopaedics, and rheumatology. He obtained his PhD from University of Utrecht, the Netherlands, under the supervision of Dr. F. Beekman. His background includes the development of statistical reconstruction algorithms for x-ray CT and scatter correction methods for cone-beam CT using accelerated Monte Carlo techniques. His experience includes industrial R&D, where his work involved the design of specialized cone-beam CT systems for image-guided surgery, ENT, and dental applications.
Assistant Professor
Department of Biomedical Engineering
Johns Hopkins University
Traylor Building, Room 624
720 Rutland Avenue
Baltimore MD 21205
Phone: 410-955-1319
Email: [email protected]
Dr. Sisniega is a Faculty Research Associate in the Department of Biomedical Engineering at Johns Hopkins University working on multimodality high-resolution imaging systems for small animal imaging (PET-CT, SPECT-CT, and FDOT-CT), for which Dr. Sisniega played a significant role in the design, development, and optimization of the high-resolution Cone-Beam CT (CBCT) component of the imaging system. His expertise includes system design and characterization through analytical modeling and Monte Carlo simulation techniques using GPU-based parallelization, and algorithm design for CBCT image processing, artifact compensation and 3D model-based image reconstruction.
His current work is focused on improvement of image quality in cone-beam CT through algorithmic approaches for: i) high-fidelity, high-speed, artifact correction, ii) volumetric image reconstruction methods for mitigation of noise and sparse sampling effects, and iii) acceleration of optimization methods to bring advanced model-based iterative reconstruction to runtimes acceptable for clinical practice. This work comprises comprehensive artifact correction methods in soft-tissue CBCT (with application to brain imaging in traumatic brain injury scenarios), including compensation of detector non-idealities, model-based beam-hardening correction, and high-fidelity, high-speed Monte Carlo scatter correction, leveraging variance reduction and GPU parallelization to achieve competitive runtime in clinical scenarios. His last research investigated approaches for purely image-based patient motion compensation in dedicated CBCT of the extremities (undergoing rigid motion) and in more challenging scenarios involving automatic compensation of deformable motion in soft-tissue CBCT.
Faculty Research Associate.
Dept. of Biomedical Engineering
Johns Hopkins University
600 N. Wolfe Street
Baltimore, MD 21287
Dr. Ali Uneri, interim co-director of the Carnegie Center, is a faculty research associate at Johns Hopkins working on development of algorithms and systems for computer-assisted, image-guided, and robotic surgery. Research areas of interest include: (1) model-based and data-driven multidimensional image registration; (2) hardware and software systems integration for image-guided interventions; and (3) incorporation of imaging and image guidance in surgical robotics.
Faculty Research Associate.
Dept. of Biomedical Engineering
Johns Hopkins University
600 N. Wolfe Street
Baltimore, MD 21287
Wojciech Zbijewski, Ph.D
Alejandro Sisniega-Crespo, Ph.D.
Ali Uneri, Ph.D.
Clinical Research
Dr. Henry Brem is the Harvey Cushing Professor of Neurosurgery at The Johns Hopkins University, Chairman of the Department of Neurosurgery, and Neurosurgeon-in-Chief. He also is a professor of Oncology, Ophthalmology, and Biomedical Engineering. Dr. Brem has developed new tools and techniques that have changed the field of neurosurgery. He carried out the pivotal clinical study that introduced navigational imaging into the neurosurgical suite. His work led to the FDA's approval of the first image guidance computer system for intraoperative localization of tumors. Furthermore, he has changed the surgical armamentarium against brain tumors by inventing and developing Gliadel® wafers to intraoperatively deliver chemotherapy to brain tumors. His work has shown that surgeons can accurately deliver potent therapies directly at the tumor site.
Harvey Cushing Professor
Professor of Neurosurgery, Ophthalmology, Oncology and Biomedical Engineering
Chairman, Department of Neurosurgery
Johns Hopkins University School of Medicine
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287
Dr. Cohen is the director of the Johns Hopkins Division of Pediatric Neurosurgery and the Benjamin S. Carson Sr., M.D., and Dr. Evelyn Spiro, R.N., Professor of Pediatric Neurosurgery. He is president of the Society of Neurological Surgeons and immediate past president of the American Society of Pediatric Neurosurgeons, and he serves as a director of the American Board of Neurological Surgery and the American Board of Pediatric Neurological Surgery. Dr. Cohen is a leader in developing minimally invasive techniques to enhance the safety and efficacy of selected pediatric neurosurgical procedures. To that end, his lab focuses on new instruments and techniques for minimally invasive surgery. He has authored 170 peer-reviewed journal articles and book chapters, and published two textbooks.
Director of the Johns Hopkins Division of Pediatric Neurosurgery
Professor of Neurosurgery
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287
Dr. Groves is a pediatric neurosurgeon and an Assistant Professor of Neurosurgery who treats children with brain and spinal cord tumors, Chiari Malformations, myelomeningocele, spacticity and epilepsy. She also focuses on spinal deformity and spinal oncology. Dr. Groves works closely with engineers on various research projects including a number of clinical trials.
Assistant Professor of Neurosurgery
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287
Dr. Robert Liddell is an Assistant Professor of Radiology and Surgery at the Johns Hopkins School of Medicine. His specialty is interventional radiology, with an expertise in interventional oncology and vascular and interventional radiology. Dr. Liddell received his MBBCh at the Royal College of Surgeons in Ireland. He completed his residency at Johns Hopkins University School of Medicine in Diagnostic Radiology and his fellowship in Interventional Radiology.
Assistant Professor of Radiology and Radiological Science
The Johns Hopkins Hospital
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287
Henry Brem, M.D.
Alan R. Cohen, M.D.
Mari Groves, M.D.
Robert Patrick Liddell, M.B.B.Ch., M.D., M.S.
Dr. Sheng-fu "Larry" Lo is a neurosurgeon specializing in primary and metastatic tumors of the spinal column, sacral tumors, spinal cord tumors, disorders of spinal alignment and degenerative spine disease. His research focuses on understanding the biology and clinical outcomes of spinal tumors, and new surgical procedures and innovative technology to improve patient safety and spinal fusion. His research has received numerous awards including the Neurosurgery Chairman’s Award for Improving Patient Safety.
Assistant Professor of Neurosurgery
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287
Dr. Kelvin K. Hong is an Associate Professor in the Johns Hopkins Medicine Division of Interventional Radiology within the Department of Radiology and Radiological Science. A specialist in interventional and vascular radiology, Dr. Hong serves as the Medical Director of the Johns Hopkins Interventional Radiology Center.
Dr. Hong earned his medical degree from South Africa’s University Of Witwatersrand Medical School in Parktown. He completed a radiology residency at Parktown West’s College of Medicine/Radiology, as well as a cardiovascular/interventional radiology fellowship and diagnostic radiology residency at The Johns Hopkins Hospital.
Divisional Director
Interventional Radiology
Associate Professor
of Radiology and Radiological Science
The Johns Hopkins Hospital
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287
Dr. Mark Luciano is the director of the Johns Hopkins Cerebral Fluid Center. A renowned leader in treating hydrocephalus, Dr. Luciano is distinguished both nationally and internationally for his research and educational and clinical work in neuroendoscopy. Among his accomplishments in neuroscience research and biomedical engineering are his investigation of the cerebrovascular response to hydrocephalus and the invention of a unique device for control of intracranial pressure (ICP) pulsatility to increase blood flow. His National Institutes of Health-funded studies have explored prolonged compression and hypoxia in the brain as a result of hydrocephalus, as well as the interaction between cerebrospinal fluid and vascular systems.
Director of the Cerebral Fluid Center
Professor of Neurosurgery
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287
Dr. Greg Osgood is an assistant professor of orthopaedic surgery at the Johns Hopkins School of Medicine and Chief of Orthopaedic Trauma for the Department of Orthopaedic Surgery. His areas of expertise include orthopaedic trauma, with a special focus on fracture non-unions, pelvis and acetabular injuries, and fractures and surgical infections. Dr. Osgood is actively involved in numerous professional organizations, including being the associate editor of the Journal of Orthopaedic Trauma, a member of the AO North America Teaching Faculty, a member of the Education Committee of the Osteosynthesis and Trauma Care Foundation, Orthopaedic Trauma Association Military Committee, and the director of the Humanitarian Program of the Osteosynthesis and Trauma Care Foundation.
Chief, Orthopaedic Trauma, Department of Orthopaedic Surgery
Assistant Professor of Orthopaedic Surgery
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287
Sheng-fu Lo, M.D.
Kelvin Kai-wen Hong, M.B.B.Ch., M.B.B.S.
Mark Luciano, M.D.
Greg M Osgood, M.D.
Dr. Daniel Michael Sciubba is a professor of neurological surgery, oncology and orthopaedic surgery at the Johns Hopkins University School of Medicine. He serves as Director of spine tumor and spinal deformity research in the Department of Neurosurgery and Director of minimally invasive spine surgery. He specializes in the surgical treatment of complex spinal conditions including tumors, degenerative spine diseases, spinal deformities and scoliosis, employing minimally invasive techniques when possible. Dr. Sciubba’s research efforts focus on patients with complex spinal conditions, most notably spinal tumors and spinal deformity.
Director, Spine Tumor and Spine Deformity Research
Professor of Neurosurgery
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287
Dr. Babar Shafiq is a board certified, fellowship trained orthopaedic surgeon who specializes in orthopaedic traumatology. As an Assistant Professor of Orthopaedic Surgery at the Johns Hopkins University School of Medicine and the Johns Hopkins Hospital, Dr. Shafiq cares for patients with challenging acute injuries and a wide variety of chronic problems secondary to trauma. He serves as the Director of the Johns Hopkins Orthopaedic Bone Health Center where he partners with Andra Love, PA-C to identify and manage the care of patients with fragility fractures and osteoporosis related fracture risk.Dr. Shafiq is the Physician Lead for the Orthopaedic Inpatient Advanced Practice Providers and he serves as the Physician Champion for the Orthopaedic inpatient Comprehensive Unit-Based Safety Program. In addition, Dr. Shafiq serves as a member of the Johns Hopkins Value Analysis Committee where he advises on the acquisition and purchase of operating room equipment, devices and implants for a multitude of surgical subspecialties.
Director
Orthopaedic Bone Health Center, Assistant Professor of Orthopaedic Surgery
601 N. Caroline St.
Baltimore, MD 21287
Dr. Clifford Weiss is an Associate Professor of Radiology and Radiological Science. He also holds appointments in Surgery and Biomedical Engineering. Additionally, he serves as Medical Director of the Johns Hopkins Center for Bioengineering Innovation and Design (CBID).
Dr. Weiss’ clinical focus lies in vascular and interventional radiology. He specializes in the diagnosis and treatment of vascular malformations, including pulmonary arteriovenous malformations and hereditary hemorrhagic telangiectasia; varicoceles; MRI-guided interventions, especially for the treatment of vascular malformations; advanced venous interventions; and advanced biliary interventions.
Dr. Weiss' research focuses primarily on the preclinical and clinical development of Bariatric Embolization, a new endovscular procedure designed to help fight obesity.
Medical Director, The Johns Hopkins Center for Bioengineering, Innovation and Design (CBID)
Director of the Interventional Radiology Research
Co-Director of the Johns Hopkins Vascular Anomalies Center
Co-Director of the Johns Hopkins HHT Center of Excellence
Associate Professor of Radiology and Radiological Science
Associate Professor of Biomedical Engineering
1800 Orleans Street
Sheikh Zayed Tower
Baltimore, MD 21287
Dr. Timothy Witham is a professor of neurological surgery and orthopaedic surgery at the Johns Hopkins University School of Medicine. His interests include the surgical treatment of degenerative conditions of the cervical and lumbar spine, including instrumented fusion procedures. He also has an expertise in the treatment of spinal tumors, spinal trauma and spinal deformity. Dr. Witham's research interests include finding novel ways to achieve spinal fusion and improving surgical techniques in the aging spine. Dr. Witham is a co-author of more than 170 peer-reviewed articles and abstracts.
Director, the Johns Hopkins Neurosurgery Spinal Fusion Laboratory
Professor of Neurosurgery
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287
Dan Sciubba, M.D.
Babar Shafiq, M.D., M.S.
Clifford Raabe Weiss, M.D.
Timothy Witham, M.D.
Department of Biomedical Engineering
Department of Neurosurgery
Johns Hopkins School of Medicine